Prediction and odds analysis for Liverpool vs Manchester United at 22:30 on October 19, Premier League round

Prediction and odds analysis for Liverpool vs Manchester United at 22:30 on October 19. Forecast of the result, expected lineups, and expert insights for the Premier League Round 10 clash between Liverpool and Manchester United.

Preview of Liverpool vs Manchester United

90-minute odds: 0 : 1

Total goals: 3.25

Liverpool is facing its worst stretch since Arne Slot became manager. After an enthusiastic start, they unexpectedly slumped with three straight defeats to Crystal Palace, Galatasaray, and Chelsea. The problem is not only the results but also their playstyle – lacking control and vulnerable at crucial moments. Mohamed Salah’s performance has declined, key players like Conor Bradley and Ibrahima Konate are injured or overworked, while new signings like Florian Wirtz and Alexander Isak have yet to fully integrate. Still, Anfield remains a massive psychological boost. The pressure is intense, as continued losses could lead Liverpool to a four-match losing streak for the first time in almost 40 years.

Manchester United arrive in Merseyside as underdogs – but with some hope. Coach Ruben Amorim’s squad is inconsistent and has not won two consecutive Premier League games this season, yet the win over Sunderland before the international break eased the players’ pressure. Amorim’s system is still being refined, but players like Kobbie Mainoo, Bruno Fernandes, and Benjamin Sesko are starting to gel. However, history is against them – the Red Devils last won at Anfield in 2016. Moreover, away matches are always a psychological challenge for United in big games. A draw is likely the most realistic goal.

Liverpool and Manchester United always produce unpredictable matches regardless of form. In their last five meetings, both teams have two wins and one draw each, including several dramatic score chases. Liverpool holds a slight advantage due to home ground and more consistent play, but United has frequently troubled them with physical play and quick counterattacks. History does not clearly favor either side – but the intensity at Anfield could be decisive.

Squad status for Liverpool vs Manchester United

Liverpool: Absent: Alisson, Wataru Endo, Giovanni Leoni. Konate and Gravenberch are doubtful.

Manchester United: Lisandro Martinez is not ready to play, Mazraoui has just returned to light training.

Expected lineups for Liverpool vs Manchester United

Liverpool: Mamardashvili; Bradley, Konate, Van Dijk, Kerkez; Szoboszlai, Jones; Salah, Wirtz, Ekitike; Isak

Manchester United: Lammens; Yoro, De Ligt, Shaw; Amad, Mainoo, Fernandes, Dorgu; Mbeumo, Cunha; Sesko

Recent form of Liverpool

04/10/2025: Chelsea 2 - 1 Liverpool (Premier League)

01/10/2025: Galatasaray 1 - 0 Liverpool (Champions League)

27/09/2025: Crystal Palace 2 - 1 Liverpool (Premier League)

24/09/2025: Liverpool 2 - 1 Southampton (Premier League)

20/09/2025: Liverpool 2 - 1 Everton (Premier League)

Recent form of Manchester United

04/10/2025: Manchester United 2 - 0 Sunderland (Premier League)

27/09/2025: Brentford 3 - 1 Manchester United (Premier League)

20/09/2025: Manchester United 2 - 1 Chelsea (Premier League)

14/09/2025: Manchester City 3 - 0 Manchester United (Premier League)

30/08/2025: Manchester United 3 - 2 Burnley (Premier League)

Recent head-to-head between Liverpool and Manchester United

05/01/2025: Liverpool 2 - 2 Manchester United (FA Cup)

01/09/2024: Manchester United 0 - 3 Liverpool (Premier League)

04/08/2024: Manchester United 0 - 3 Liverpool (Friendly)

07/04/2024: Manchester United 2 - 2 Liverpool (Premier League)

17/03/2024: Manchester United 4 - 3 Liverpool (FA Cup)

Prediction for Liverpool vs Manchester United

Liverpool has home advantage but their poor form makes it difficult to fully dominate. Manchester United can pose challenges, but their resilience at Anfield remains uncertain.

Predicted score: Liverpool 2 - 1 Manchester United